Ctat`I Victor D.Rosenthal, Sandra Guzman, Christopher Crnich “Device-Associated Nosocomial Infection Rates in Intensive Care Units”, opublikovannoj in magazine “Infection control and On materials Hospital Epidemiology”, Vol.25, N3, 2004, pp. 251-255. When in 1970 US FDA (Food and Drug Administration) the United States of America has approved containers for vnutrivennogo introductions of solutions VIAFLEX (Viafleks) company "Bakster" manufactures, eto became the present revolution in technology of intravenous therapy.

As the first-ever plastic container for intravenous solutions, VIAFLEX obladal a number of essential advantages before glass capacities for rastvorov. Most significant of them was that the plastic container nelzja to break, expenses for transportation and recycling are smaller.

  Other advantage less appreciable, but not less important, is nevozmozhnost air hits in flexible fallen down at vytekanii liquids kontejner as it occurs at use glass or plastic flakonov. The exception of possibility of hit of air in system does nevozmozhnym infitsirovanie the patient at intravenous infusion.

  the Closed sterile fallen down systems for intravenous solutions which vkljuchajut also minicontainers (50 and 100 ml) for additional carrying out lekarstvennoj therapies, quickly became the industrial standard in Northern Amerike and other parts of the world. The USA completely have passed to use such zakrytyh systems from the middle of the seventieth years.

  Nevertheless, despite set of the researches which have proved success primenenija of closed systems in preventive maintenance infitsirovanija of patients, in many stranah open systems (for example, in Southern Africa-80 of % bolnits till now are used!) Is even worse business in Russia where to risk infitsirovanija through air v open systems the risk infitsirovanija at the expense of bad sterilisation pri intrahospital manufacture of solutions is added is.

  One of the reasons of such state of affairs is the price. Certainly, closed gibkie systems are more expensive than the glass and plastic bottles which are let out frequently silami of local manufacturers or intrahospital drugstores. In many countries ne always understand advantages of the closed systems and wish to have proofs, chto these systems will be applied successfully also in their conditions by experts mestnyh clinics, as well as in other countries of the world.

Cpecial`nymi mnogotsentrovymi by researches in Argentina, Brazil and a number drugih the countries it is proved, that application of the closed systems can not only lower chastotu infitsirovanija the patients, defined in cases of hit of an infection in krovjanoe a channel, and thus to reduce death rate, but also considerably to reduce rashody to the treatment connected with arising complications at application otkrytyh of systems.

the Governments of developing countries should understand, that a small prize in tsene at use of open systems (stekljanye or plastic bottles), oborachivaetsja the big expenses because of necessity of the subsequent application antibiotikov and other antibacterial preparations for treatment arising oslozhneny infectious character, and also increase in term of stay of the patient na to a hospital cot ».

  These advantages of the closed systems (plastic self-fallen down bags) otchetlivo have been shown in leading clinics of the several countries of the world. Such issledovanija which results opublikovany in serious medical magazines are spent in branches of intensive therapy (OIT) two hospitals Argentiny, three hospitals of Mexico and Brazil and Italy. Careful monitoring mikrobiologicheskogo has shown blood statuses, that application of open systems soprovozhdalos infitsirovaniem blood on the average in 48 cases on 1000 put tsentralnyh vascular kateterov (TSSK).

After introduction to practice frequency of the closed systems of infecting is in four, separations in Argentina went intensive therapy down by 3 on 1000 CSK. for North America of standards and most developed countries does from 0 to 8 cases on 1000 CSK. These indexes as impossible testify more expressly to transition necessity and other countries, including Russia, to applied exceptionally to the closed systems, it is a task, to declare importance.

 Unfortunately, in Russia there is not strict infectious control after by the state of blood for patients which infuzionnaya therapy is conducted, and the results of blood-poisoning show up frequently in remote terms, that not allows to bind it to the conducted intravenous therapy. A situation is aggravated by until now existent practice of in-hospital preparation of solutions, that in a yet greater degree promotes the risk of hit of exciters infectious diseases in solutions for injections and further in blood of patients.

The arguments resulted higher to a full degree behave not only to base to solutions for intravenous introduction (izotonicheskie solutions of chloride of sodium and glucose, solution of Ringera and other), but also to preparations for a parenterally feed (solutions of amino acid, lipophilics, concentrated glucose). As a parenterally feed is appointed heavy enough patients (vast burns, states after heavy operations et cetera), to incapable of independent to the enteral`nomu eating, the risk of infecting for them is especially great from a decline immunity. Unfortunately, presently at the market of parenterally feed in The even leading European producers offer to Russia exceptionally opened (in glass small bottles) systems, containing lipophilics and solutions amino acid.

Research in a number of anchorwomen of foreign clinics rotined that general percent errors for hospitals makes 9% (Flynn & al 1997). Most typical errors - errors are in the dosage of preparations. Solutions have for a parenterally feed the greatest level of errors - 37% at preparation by hand and 22% at partly automated preparation. From each 100 errors 2 have objectively important clinical value.

Risk of infecting and influence on the cost of treatment at application of mixtures in multicontainer B/Ss (when three basic components of parenterally feed - the amino acid, fats and glucose are in one sack, part on three sections with the subsequent mixing of components) and in glass small bottles (where every component is entered separately) compared in research of Durand (1997), and the results of all of researches of for some time past in this direction are generalized in review of Achach and sovtorami (2002). Farmako-economic model, applied in this research, rotined that complete parenterally feed (PPP) in B/Ss can give such advantage which the decline of daily risk is arrived at at нozokomial`noy bakteriemii to the threshold in 0,3%. Such decline corresponds umen`sheniyu risk of infecting on 50-60% for patients in the separation of intensive therapies.

Thus total worth of treatment on one patient at the use multicontainer B/Ss was on 12-23% below, than cost of treatment preparations in glass small bottles. Thus, application of the closed systems reduces death rate for patients, frequency of infecting of blood, abbreviates the terms of stay on a hospital bunk and substantially saves a money on treatment. These circumstances dictate the necessity of the quickest passing to the closed systems of introduction solutions.

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